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J. Schott

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Open access Aug 2026

Amyloid-PET pipeline choice influences classification of preclinical Alzheimer's disease

The findings highlight the importance of considering cut-point uncertainty and methodological influences when interpreting early-stage amyloidosis and highlight the importance of considering cut-point uncertainty and methodological influences when interpreting early-stage amyloidosis.

W. Coath, A. Bollack, C. Scott et al. · 0 citations
Open access Jul 2026

Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.

A double-cutoff analysis suggest that scans in the 11 to 26 Centiloid range should be interpreted with caution depending on the context of use, and positivity cutoffs converged around 18 Centiloids (data-driven) and 27 Centiloids (visual reads).

G. Blazhenets, D. Soleimani-Meigooni, Konstantinos Chiotis et al. · 5 citations
Open access Jul 2026

Performance of Alzheimer Disease Plasma Biomarkers in Patients With Prion Diseases

This study provides Class II evidence that plasma NfL/p-tau217 discriminates patients with CJD from those with AD and Diagnosing AD with a single abnormal p-tau plasma biomarker risks misdiagnosing prion diseases as AD.

Thomas Coysh, Rhiannon Laban, Elena Veleva et al. · 0 citations

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