National trends of unique-PCV20 / PCV21 serotypes, common PCV20-PCV21 and non-vaccine serotypes causing invasive pneumococcal disease in adults in Spain during the period 2009-2026
This study emphasizes the rapid re-emergence of infections caused by traditional PCV7 serotypes especially serotypes 4 and 14 and reinforce the idea that the use of broader PCVs must be accompanied by an increase in the uptake rates in adults of all ages.