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Author

J. Seymour

h-index 17 View on Semantic Scholar

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Open access Sep 2026

Dynamic risk stratification using early CAR-T expansion in R/R LBCL treated with axicabtagene ciloleucel.

The clinical utility of routine monitoring of chimeric antigen receptor (CAR) T-cell expansion post-infusion remains controversial. We conducted a retrospective analysis of a prospectively collected cohort of 176 patients with relapsed/refractory large B-cell lymphoma (LBCL) treated with axicabtagene ciloleucel (axi-ce...

Brydon Panozzo, S. Robinson, A. Minson et al. · 0 citations
Review Jul 2026

CRISPR in clinical oncology: translational advances from molecular diagnostics to therapeutics.

How CRISPR-enabled functional genomics approaches can reveal unexpected cancer dependencies and resistance mechanisms is outlined, and emerging applications of CRISPR-based diagnostics in oncology that convert precise nucleic acid sequence recognition into rapid mutation detection are discussed.

S. Grigg, Carolyn Shembrey, M. Fareh et al. · 1 citation

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