Review
Sep 2026
Prekallikrein: the catalytic crossroads of inflammation and thrombosis
Purpose of review The contact activation pathway, historically considered dispensable for hemostasis, has re-emerged as a critical mediator of thromboinflammation. Plasma prekallikrein, through its activation to kallikrein, links coagulation, inflammation, and vascular biology. This review is timely given increasing in...
Aditya K. Malhotra, Arjun Tomer, Ocean Punsalan et al.
· Current opinion in hematolog... · 0 citations