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Open access Sep 2026

Differential Cancer Risks and Noninvasive Predictors in MASLD, MetALD, and ALD: A Longitudinal Analysis

Background/Aims The recently proposed classification of steatotic liver disease (SLD) comprises metabolic dysfunction-associated steatotic liver disease (MASLD), MASLD with increased alcohol intake (MetALD), and alcohol-related liver disease (ALD). Long-term cancer risk across these phenotypes remains incompletely char...

Hana Park, Ji-Young Lee, J. E. Koo et al. · 0 citations
Open access Aug 2026

Combined hepatocellular-cholangiocarcinoma shows distinct recurrence patterns and poorer postoperative outcomes compared to hepatocellular carcinoma

Combined hepatocellular–cholangiocarcinoma (cHCC-CCA) is an uncommon primary liver cancer with distinct histology but overlapping clinical features with hepatocellular carcinoma (HCC). This study compared postoperative outcomes between cHCC-CCA and HCC in patients with very-early or early-stage tumors. We re...

Yeongseok Hwang, Subin Heo, Y. Yoon et al. · 0 citations
Open access Sep 2026

Clinical features, treatment patterns, and outcomes of young-onset hepatocellular carcinoma: a tertiary cohort analysis with a nationwide population-based study.

Background/Aims Hepatocellular carcinoma (HCC) in younger patients is uncommon, and its clinical behavior and prognosis remain unclear. We aimed to evaluate the characteristics, treatment patterns, and outcomes of young-onset HCC using large-scale datasets. Methods This study analyzed two cohorts: the Asan Medical Ce...

Eunju Kim, Min Young Kim, Jina Park et al. · 0 citations

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