Author

J. Stamatoyannopoulos

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CHROMATIN SEQUENCING Single-molecule regulatory architectures captured by chromatin fiber sequencing

Fiber-seq exposed widespread plasticity in the linear organization of individual chromatin fibers and illuminated principles guiding regulatory DNA actuation, the coordinated actuation of neighboring regulatory elements, single-molecule nucleosome positioning, and single-molecule transcription factor occupancy.

Andrew B. Stergachis, Brian M. Debo, E. Haugen et al. · 0 citations

Open access Jul 2026

An encyclopedia of human enhancer–gene regulatory interactions

An encyclopedia of enhancer–gene regulatory interactions in the human genome is built, revealing global properties of enhancer networks, identifying differences in regulatory complexity across genes, and improving analyses linking noncoding variants to target genes and cell types for common, complex diseases.

A. Gschwind, Kristy S. Mualim, Alireza Karbalayghareh et al. · Nature · 6 citations