Author

J. Taieb

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Review Open access Sep 2026

Early-Onset Colorectal Cancer: Clinical and Molecular Features with Emerging Insights from Comprehensive Genomic Profiling.

Early‑onset colorectal cancer (EOCRC), defined as colorectal cancer (CRC) diagnosed before 50 years of age, is increasing globally. Colorectal cancer is currently the third most commonly diagnosed cancer and the second leading cause of cancer-related death worldwide, with GLOBOCAN 2024 estimating approximately 2.04 mil...

A. Nogueira, Jennifer Brondon, Konstantin Haradinov et al. · Oncology and Therapy · 0 citations

Open access Aug 2026

Usability and relevance of specialized population-based cancer registry data in externally controlled trials.

BACKGROUND Randomized clinical trials are becoming very challenging to perform in oncology both in rare cancers and in more common cancers, fragmented according to molecular characteristics. OBJECTIVE In this proof of concept, we tested the feasibility of using data from a specialized digestive cancer registry as an...

V. Jooste, A. Bouvier, C. Lepage et al. · Journal of Clinical Epidemio... · 0 citations

Aug 2026

Baseline circulating and tumor γδ T cells and early circulating CD8⁺PD1⁺ expansion predict response to Atezolizumab-bevacizumab in HCC.

BACKGROUND We aimed to identify circulating and tumor immune features predictive of oncological outcomes under Atezolizumab-Bevacizumab (AtezoBev) therapy for hepatocellular carcinoma (HCC). METHODS We conducted a prospective study in 31 patients treated with first-line AtezoBev, integrating sequential PBMC immunophe...

I. Galy-Fauroux, A. Asif-Laidin, M. Evain et al. · Clinical Cancer Research · 0 citations