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Author

J. Tinker

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2 papers indexed here

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Open access Aug 2026

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

Chronic infection is important for the transmission of Salmonella enterica serovar Typhi (S. Typhi), an obligate human pathogen responsible for typhoid fever. The immunomodulatory action of typhoid toxin helps establish an initial stealth invasion of the intestinal tract that can lead to systemic spread, colonization o...

Maria C. Zabala-Rodriguez, J. Tinker, Teresa Frisan et al. · 0 citations
Open access Sep 2026

Multi-Omics and Functional Analysis of Salmonella ArtAB Toxin Activity Reveals Transcriptomic Remodeling and Epithelial Barrier Dysfunction

AB5 toxins are important virulence factors produced by Gram-negative bacteria and have been identified in many non-typhoidal Salmonella (NTS) serovars; however, their effects on host cell signaling and epithelial barrier function remain poorly understood. This study characterized the molecular and functional effects of...

N. Souza, Alexander O. Hale, R. S. Beard et al. · 0 citations

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