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J. Tong

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Open access Oct 2026

TMEM65 ameliorates post-myocardial infarction heart failure by maintaining mitochondrial calcium homeostasis via inhibiting NCLX ubiquitination

Disruption of mitochondrial calcium homeostasis drives post-myocardial infarction (MI) heart failure by impairing excitation-contraction coupling . However, the critical upstream molecular mechanisms remain unclear, necessitating novel interventional targets. To elucidate the core mechanisms driving cardio...

S. Li, J. Tong · 0 citations

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