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J. V. Silva-Silva

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Open access Sep 2026

Bioactivity-Guided Optimization of 3-Deoxyanthocyanidin Extraction and Seasonal Mapping of Four Morphotypes of Fridericia chica (Bonpl.) L.G. Lohmann

Ultrasound-assisted extraction (UAE) was combined with a design of experiments (DoE) to optimize the recovery of 3-deoxyanthocyanidins (3D-anths) from Fridericia chica leaves using in vitro antileishmanial activity against Leishmania amazonensis promastigotes as a bioactivity-guided response. A 3 × 3 factorial design e...

Paulo Victor R. Souza, Y. J. Ramos, J. V. Silva-Silva et al. · 0 citations

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