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Author

J. V. van Gerven

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Open access Sep 2026

Safety, pharmacokinetics, and pharmacodynamics of intravenously administered deuterated N,N-dimethyltryptamine (CYB004) in healthy volunteers.

BACKGROUND Serotonergic psychedelics, such as N,N-dimethyltryptamine (DMT), have shown therapeutic potential in various psychiatric disorders. However, DMT demonstrates pharmacokinetic (PK) variability and a short half-life. AIMS This exploratory study investigated the PK, pharmacodynamic (PD), and safety profile of...

K. V. van der Heijden, Gabriël E. Jacobs, Ellen James et al. · 0 citations

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