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Author

J. V. Van Raamsdonk

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Sep 2026

High confidence HIF-1 target genes for quantifying the activation of the HIF-1-mediated hypoxia response

The hypoxia-inducible factor 1 ( HIF-1 )-mediated hypoxia response is an evolutionarily conserved stress response that enables adaptation to conditions of low oxygen and mitochondrial dysfunction. This pathway has been shown to affect both stress resistance and longevity. HIF-1 activity is regulated by EGL-9 , VHL-1 ,...

Camille Ah Desnos, Aura A. Tamez González, J. V. Van Raamsdonk · 0 citations

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