DNA methylation deregulation is an essential feature of tumor biology, influencing cancer formation and pathogenesis. Analyses of DNA methylation in bulk cancer specimens are challenging due to the high data dimensionality, noise, and mixture of different cell types. Here, we characterized methylation dynamics in cance...
Iñaki Sasiain, D. F. Nacer, M. Jönsson et al.· npj Breast Cancer· 1 citation
ABSTRACT Thyroid function has been suggested to be associated with breast cancer risk, but not much is known about thyroid hormones as a potential prognostic factor for breast cancer. This study investigated the relation between thyroid hormones in breast cancer patients and mortality. A total of 2000 breast cancer pat...
Annie Brange, Ylva Heyman, Kamil Demircan et al.· Cancer Medicine· 0 citations
Integration of longitudinal clinical data with molecular profiling enabled characterization of real-world treatment patterns, long-term outcomes, molecular subtypes, risk-of-recurrence, and the somatic mutational landscape in this population-based cohort.
L. Saal, H. Dalal, P. Meng et al.· medRxiv· 0 citations
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