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Aug 2026

Aptamer-functionalized silver nanoparticle pre-analytical enrichment integrated with loop-mediated isothermal amplification for improved detection of pathogenic Leptospira interrogans.

Early diagnosis of leptospirosis remains challenging because the low and transient leptospiraemia during the acute phase often results in bacterial DNA concentrations below the analytical detection limit of conventional molecular assays. This proof-of-concept study evaluated the feasibility of integrating aptamer-funct...

Shubham Khutwada, P. Deepa, V. Shyma et al. · 0 citations
Jul 2026

Unravelling cryptic phosphonate biosynthesis in Chelatococcus asaccharovorans through genome mining.

Phosphonates are chemically distinctive natural products characterized by a stable carbon-phosphorus (C-P) bond and are traditionally associated with a limited number of well-studied bacterial genera. We performed comparative genome mining of four publicly available Chelatococcus asaccharovorans genomes along with rela...

V. Solairathi, J. Vergis, V. K. Vinod et al. · 0 citations

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