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Author

J. Virgen-Ortíz

1 paper indexed here

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Open access Oct 2026

Evaluation of Dihydropyridine Derivatives as Aldose Reductase Inhibitors: Enzymatic Screening, Molecular Docking and Ex Vivo Assessment of a Selected Compound in a Lens Model

Aldose reductase (AR) is a key enzyme in the polyol pathway and has been widely implicated in the development of diabetic complications, including cataract formation. In this work, a series of structurally modified 1,4-dihydropyridine (DHP) derivatives were evaluated as potential AR inhibitors. The compounds were obtai...

K. L. Alonso-Hurtado, Tania Méndez-Pérez, Z. Hernández-Gallegos et al. · 0 citations

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