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Author

J. W. Harper

2 papers indexed here

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Open access Nov 2026

Components of an ESCRT-independent nuclear envelope assembly pathway.

In many cells, the nuclear envelope (NE) must be reassembled after mitosis, and holes in the nuclear membrane must be sealed. During NE assembly, the NE-specific adaptor, Cmp7, recruits/activates endosomal sorting complex required for transport (ESCRT)-III proteins to mediate NE sealing. However, recent evidence sugges...

Emma M. Sydir, M. Farra, Abigail L. Whitford et al. · 0 citations
Open access Jul 2026

Structural Mechanisms of DNAJC13 Dimeric Assembly and InsP6 binding in Recycling Endosome Regulation

It is shown that DNAJC13 forms an unexpected antiparallel homodimeric architecture involving distinctive symmetrical interactions between composite IWN1 and α-solenoid ARM2 domains in each protomer, which provides a structural and mechanistic framework for understanding DNAJC13 function in recycling endosome control.

Tao Fu, Chan Lee, Frances V. Hundley et al. · 0 citations

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