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Review Open access Sep 2026

The MTRNR2L gene family and age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in aging adults, yet no FDA-approved therapies exist for early and intermediate disease. Multiple interconnected pathways, including mitochondrial dysfunction, oxidative stress, and inflammation, contribute to retinal pigment epithelium (RPE) dege...

Adam Moosa, J. Wang, Margaret M. DeAngelis et al. · 0 citations

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