SGLT2 inhibition, uric acid and inflammation in glycemic burden-related progression of cardiac autonomic neuropathy in type 2 diabetes mellitus: insights from machine learning and mediation analysis
Objective To identify independent predictors of diabetic cardiac autonomic neuropathy (DCAN) deterioration in patients with type 2 diabetes mellitus (T2DM), develop machine learning (ML)-based risk prediction models, and explore the underlying mediation of glycemic burden. Methods This prospective cohort study included...