J. Zheng

AI-Empowered Multimodal Data Integration and Knowledge Discovery for Pharmacovigilance

Reconstructing synthetic hearts from ECG using flow matching

Cardiac imaging enables quantitative assessment of cardiac structure and function but remains constrained by cost, infrastructure and specialist expertise. In contrast, electrocardiogram (ECG) is widely accessible yet underexploited, despite encoding latent information about cardiac physiology. Here we introduce vision...

Disease progression Mendelian randomization of risk factors for kidney function decline in chronic kidney disease and the general population

Introduction With limited treatment options, identifying risk factors for chronic kidney disease (CKD) disease progression is an important aspect of CKD management. Novel approaches for correcting case-only genome-wide association studies (GWAS) for index event bias and the availability of large GWAS conducted in peopl...