Open access
Sep 2026
The Circadian Clock Component NPAS2 is modulated by AMPK and Regulates Substrate Utilization and Mitochondrial Function in Human Skeletal Muscle Cells.
The molecular circadian clock coordinates cellular and systemic metabolism across the day, yet how it integrates with energy-sensing pathways in human skeletal muscle remains incompletely understood. AMP-activated protein kinase (AMPK) functions as a cellular energy sensor and has been implicated in circadian regulatio...
David Rizo-Roca, Logan A. Pendergrast, Prasad G. Kamble et al.
· Molecular Metabolism · 0 citations