Open access
Aug 2026
Coronavirus NSP14 drives internal m7G modification to rewire host splicing and promote viral replication
Using SARS-CoV-2 infection models, it is shown that viral replication is associated with increased cellular m7G signal, supporting the relevance of this pathway during infection and suggesting that NSP14-induced m7G modification may contribute to the remodeling of host gene expression during coronavirus infection.
Ensueño Esmeralda Sáenz Altamirano, Chien-Hsin Huang, Yueh-Lin Tsai et al.
· Nucleic Acids Research · 0 citations