Jacopo Cardellini

Lipoprotein Corona Reshapes the Internal Structure of Lipid Nanoparticles

Lipid nanoparticles (LNPs) are central to nanomedicine, yet their clinical translation is limited by the difficulty of predicting structure-bioactivity relationships. Although the biomolecular corona is known to define the nanoparticle biological identity by modifying surface properties, its effect on internal nanopart...