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Jae Hee Cheon

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Open access Aug 2026

Efficacy and safety of upadacitinib for Crohn's disease in patients in East Asia: a post hoc analysis of randomized phase 3 studies.

BACKGROUND Upadacitinib is an oral Janus kinase inhibitor approved for the treatment of moderate-to-severe Crohn's disease (CD). This post hoc analysis reports the efficacy and safety of upadacitinib for CD in patients in East Asia enrolled in the phase 3 clinical trials. METHODS In two induction studies (U-EXCEL [NC...

Min-Hu Chen, Xiang Gao, Kenji Watanabe et al. · 0 citations
Open access Sep 2026

Population-specific rare variants influence age at diagnosis in Korean inflammatory bowel disease

Background/Aims Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis (UC), is increasing in East Asia. Most known susceptibility loci, identified primarily in Europeans, remain insufficient to explain clinical heterogeneity in Asians. We performed whole-exome sequencing in Korean...

Min-Sun Cho, DongHwan Shin, Jongwook Yu et al. · 1 citation · ⚡1

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