Author

Jae Ho Lee

2 papers indexed here

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Open access Sep 2026

Tubacin induces TFEB-dependent ferritinophagy independently of HDAC6 and sensitizes cancer cells to ferroptosis under GSH-GPX4 axis disruption.

Histone deacetylase 6 (HDAC6) is a promising therapeutic target in cancer. However, its inhibitors show limited efficacy as monotherapies and are more effective in combination settings, suggesting a context-dependent mechanism that remains poorly defined. Here, we show that tubacin sensitizes cancer cells to ferroptosi...

Gyeongmi Kim, S. Jang, Do-Gyeong Kim et al. · Biochemical Pharmacology · 0 citations

Review Jul 2026

The multifaceted role of cathepsin a in glioblastoma pathogenesis: from molecular scaffolding to immunological evasion.

Cathepsin A is best interpreted not as a validated oncogenic driver but as a lens for aggressive, mesenchymal-like and myeloid-enriched glioma states and for interpreting lysosome/CMA-associated vulnerabilities.

Jaeseok Choi, Beomwoo Lee, Chang-gue Son et al. · Cellular Signalling · 0 citations