Author

Jae-Won Huh

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Sep 2026

Identification and validation of condition-specific candidate reference genes for accurate RT-qPCR normalization in acute and chronic methamphetamine-exposed cynomolgus monkeys.

Reverse transcription quantitative real-time PCR (RT-qPCR) is widely used to quantify gene expression, but its accuracy depends on appropriate normalization using stable reference genes (RGs). Because methamphetamine (METH) exposure induces widespread transcriptional changes, conventional housekeeping genes may not rem...

Sang-Je Park, Se-Hee Choe, Hyeon-Mu Cho et al. · Neurotoxicology · 0 citations

Open access Aug 2026

Dual-mode SOX2 regulation by miR-150 via mRNA suppression and autophagy controls stem cell fate

A role for miR-150 deficiency in biasing ectoderm–mesoderm lineage specification in hPSCs is defined and SOX2 is identified as a key downstream node regulated primarily through altered mRNA stability, with additional involvement of an autophagy-associated pathway.

Xing Zhen, Hyebin Koh, Dong-Seok Lee et al. · Signal Transduction and Targ... · 0 citations

Open access Jul 2026

Age- and sex- related patterns in hematobiochemical and anthropometric parameters of Macaca monkeys.

Reference indices for hematological and biochemical parameters in macaques are established, providing valuable insights into age-related changes in primate blood profiles, and revealing convergent aging markers across primates.

Hyeon-Mu Cho, S. Choe, Hye-Ri Park et al. · GeroScience · 0 citations