Author

Jakob G. Knudsen

2 papers indexed here

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Open access Sep 2026

Primary cilia coordinate c-KIT signaling induced proliferation in alpha cells

Circulating glucagon levels are elevated in patients with diabetes and obesity and contribute to hyperglycemia. The mechanisms underlying hyperglucagonemia remain poorly understood, but expansion of pancreatic α-cell mass is thought to play an important role. Primary cilia are sensory organelles that act as signaling h...

Ganga Deshar, Mariam G. Aslanyan, Gaurav D. Diwan et al. · bioRxiv · 0 citations

Open access Aug 2026

Distribution of the glucagon receptor in periventricular brain barrier interfaces including motile and primary cilia in rat brain

Glucagon is a key metabolic hormone regulating blood glucose and appetite, yet little is known about its actions within the brain. Here, we investigated its receptor (GCGR) localization in periventricular brain barrier interfaces in young rats using immunohistochemical and immunofluorescence approaches. GCGR was enrich...

C. B. Holst, O. K. Thomsen, N. Wewer Albrechtsen et al. · bioRxiv · 0 citations