Measles remains a significant source of morbidity and mortality globally. There are currently no licensed treatments for patients at high risk of severe disease. There is limited knowledge about the human antibody response to a measles infection or vaccination or the structural determinants of antibody-mediated neutral...
Laura S. Handal, E. Binshtein, Nurgun Kose et al.· Cell Reports Medicine· 0 citations
Impedance-based technologies provide a robust and objective means to quantify cytopathic effects (CPE) in cell culture monolayers, overcoming the limitations of traditional endpoint or visually subjective assays. Cytolytic viruses typically induce pronounced morphological changes and cell death in infected cultures, ma...
Ashley Zolfaghari, Naveenchandra Suryadevara, Jing Zhang et al.· Journal of Visualized Experi...· 0 citations
The successful adaptation of linking B cell receptor to antigen specificity through sequencing (LIBRA-seq) to immunized alpacas for the rapid identification of antigen-specific nanobodies, derived from heavy-chain antibodies, is demonstrated.
Sabina E. W. Leonard, Perry T. Wasdin, Katherine Webb et al.· Cell Reports Methods· 0 citations
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