James Frank

Service capacity and amyloid-related imaging abnormality burden of antiamyloid therapy for early Alzheimer’s disease: a parameterised modelling study of a one-million-person

Treated patient numbers are modest relative to the assessment volume required to identify them, and the binding constraints are diagnostic throughput and MRI capacity rather than the treatment decision itself, so investment in referral pathways and imaging capacity is likely to determine delivery more than further refi...