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Author

James M. McDonnell

1 paper indexed here

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Open access Sep 2026

Antibodies targeting a shared epitope exploit IgE allostery to drive distinct functional outcomes

This study provides a mechanistic framework for understanding how allosteric transitions modulate antibody function and suggests that prioritizing conformational capture over epitope diversity is essential for engineering next-generation therapeutics.

A. Davies, N. Drinkwater, A. Beavil et al. · 0 citations

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