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James R. Swartz

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Open access Aug 2026

Genome mining reveals a sporulation-associated protein with ferredoxin–NADP+ reductase activity in Clostridium pasteurianum: structural and kinetic characterization

Structural analysis of the beneficial mutations suggests that disruption of hydrogen bonds flanking a flexible coil propagates conformational effects to the NAD(P)H binding loops, rationalising the improved substrate affinities of the FNR superfamily.

Weigao Wang, Qian-Qiao Liu, James R. Swartz · bioRxiv · 0 citations