Development and validation of a bioanalytical hplc-dad method for ketoprofen quantification in rat plasma and brain tissue: application to pharmacokinetic studies and tissue distribution analysis
Ketoprofen (KTP) is used as an anti-inflammatory agent and has been studied as a potential treatment for neurodegenerative diseases. This study developed and validated a sensitive high-performance liquid chromatography with diode-array detection method for quantifying KTP in rat plasma and brain tissue. Sample preparat...