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Review Open access Oct 2026

B-cell modulators in immunoglobulin A nephropathy

Immunoglobulin A nephropathy (IgAN), defined by mesangial immune-complex deposition enriched for galactose-deficient IgA1 (Gd-IgA1), is the most prevalent biopsy-confirmed primary glomerulonephritis worldwide. Advances in mucosal immunobiology and genetics have underscored the role of dysregulated B-cell activity, incr...

A. Rajasekaran, Jan Novak, D. V. Rizk · 0 citations

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