Preliminary findings on the enhancement of skeletal muscle structure and function in aged male mice by P7C3 activation of nicotinamide phosphoribosyl transferase (NAMPT).
Nicotinamide phosphoribosyl transferase (NAMPT) activation is a key enzyme in the NAD+ salvage pathway that mediates major metabolic changes in skeletal muscle and during aging. The Nampt activator P7C3 provides beneficial effects to both cardiac and skeletal muscle in diabetes, but the effects on aging remain unknown....