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Author

Jane Kondev

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Open access Sep 2026

The Trajectory Statistics of Biological Exploratory Dynamics

Biological processes, from molecules diffusing to their regulatory destinations to whales pursuing food or mates, are widely exploratory. Such behaviors are effective when some verifiable functional state or outcome can be reached regardless of initial conditions. In these cases, systems repeatedly undergo distinct and...

Sara D. Mahdavi, Gabriel L. Salmon, M. Ashok et al. · 0 citations
Open access Aug 2026

Actin filament assembly driven by distributive polymerases clustered on membrane surfaces.

It is concluded that surface-mediated polymerization can outpace solution-mediated elongation, even at high actin concentrations (>100 μM); the finite time required for profilin dissociation decreases the advantage conferred by surface-associated polymerases, but only in the absence of force.

R. D. Mullins, Jane Kondev, Kristen Skruber · 0 citations

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