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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Janez Konc

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Open access Aug 2026

Conserved water molecules shape the pathogenicity of missense variants in human proteins.

It is suggested that disruption of a single CWM can contribute to long-range structural remodeling observed in a disease-associated variant, and incorporated water-mediated interactions into structural models provides a generalizable framework for interpreting human genetic variation and its contribution to disease.

Janez Konc, Karmen Recer, Tanja Kunej et al. · 0 citations
Review 2026

In Silico Laboratory: New and Updated Tools for Protein-Centered Drug Discovery.

This chapter provides an updated overview of the ProBiS tools, which identify binding sites, predict ligand interactions, and analyze conserved water molecules, and enhances the annotation of AlphaFold2-modeled human proteome structures.

D. Janežič, Janez Konc · 0 citations

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