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Author

Janice Bennett

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Open access Sep 2026

Upstream process optimization and its critical role in chimpanzee adenoviral vector clinical drug development: lessons learned from VRON-0200 manufacturing

It is argued that the bioprocessing community’s longstanding emphasis on downstream polishing overlooks the foundational role of upstream control in addressing AdC-specific hurdles, andrioritizing upstream-first strategies holds transformative potential to improve vector quality, enhance safety profiles, accelerate dev...

Larissa H. Haut, Janice Bennett, P. MacDonald · 0 citations

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