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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Janine M. Rotsides

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Review Open access Aug 2026

Convergent Mechanistic Pathways Driving the Anaplastic Phenotype in Thyroid Cancer

The principal mechanistic programs that define the ATC phenotype are described: disruption of cell-cycle and apoptotic control through alterations in TP53, CDKN2A/B, and aberrant MAPK activation; metabolic adaptations involving glycolysis, glutaminolysis, and mitochondrial one-carbon metabolism; reprogramming of canoni...

Anthony Centone, N. DeSouza, Nan Yang et al. · 0 citations

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