Janmeet S. Saini

Molecular Pathways, Target Landscape, and Translational Models in Heart Failure with Preserved Ejection Fraction

Highlights What are the main findings? HFpEF’s clinical heterogeneity is attributable to underlying interconnected molecular pathways that drive the disease, and the therapeutic landscape is evolving toward phenotype-specific interventions. Current animals and in vitro HFpEF fail to fully recapitulate the mechanistic c...