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Author

Jarne Bonroy

1 paper indexed here

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Open access Oct 2026

XIST drives X-chromosome inactivation and safeguards female extraembryonic cells in humans

X-chromosome inactivation (XCI) is essential for extraembryonic tissue growth and embryo development in mice. However, species-specific differences in its timing and regulation have left its role in human development unclear. Here, we show that the in vitro differentiation of naive human pluripotent stem cells to troph...

Amitesh Panda, L. Carrillo, B. Balaton et al. · 1 citation

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