Author

Jasmine Tat

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Open access Oct 2026

Integrative multi-omics reveals CUL4B as a modulator of macrophage pyroptosis and innate defense against Staphylococcus aureus.

Staphylococcus aureus (SA) causes a broad range of invasive human diseases, increasingly complicated by antibiotic resistance. Macrophages (MΦ) play a central role in innate immunity, yet key aspects of their interaction with SA remain incompletely understood because of the pathogen's diverse immune evasion strategies....

Fatemeh Askarian, Daniel Sun, Jasmine Tat et al. · Science Advances · 0 citations

Open access Sep 2026

SEC-seq reveals translation-focused metabolic strategies for high IgG productivity in clonal CHO cells.

Chinese hamster ovary (CHO) cells are the dominant host for therapeutic protein production, yet intra- and inter-clonal heterogeneity in manufacturing phenotypes, and the underlying metabolic and secretory circuitry, remain poorly defined at single-cell resolution. Using secretion encoded single-cell sequencing (SEC-se...

Jasmine Tat, Fides D. Lay, Jennitte L. Stevens et al. · Metabolic Engineering · 0 citations