Findings define previously unrecognized interactions between CD38 and targetable pathways and genes in T-ALL and identify rational combinatorial strategies to enhance CD38-directed therapies and reduce relapse risk.
R. Shraim, Gong-Ping Shi, Yi-Zhen Li et al.· Blood· 0 citations
The Vertebrate Regulatory MOdule Detector (VRMOD) provides a universal coordinate reference system for regulatory sequences across 309 vertebrate genomes and enables genome-wide annotation of non-coding regulatory elements in any vertebrate species using genomic sequence alone.
Tássia Mangetti Gonçalves, Casey L. Stewart, Samantha D. Baxley et al.· NAR Genomics and Bioinformat...· 0 citations
Early-phase studies of deep B cell depletion with anti-CD19 chimeric antigen receptor (CAR) T have produced prolonged, drug-free remission in refractory autoimmune disease. However, CAR T cell therapy requires lymphodepleting chemotherapy, autologous cell manufacturing and specialized infrastructure, limiting reach to...
Jason Xu, Chun-Li Mei, Xin Guan et al.· Nature Medicine· 0 citations
We introduce WC2026-Agents, a benchmark and dataset for evaluating large language models (LLMs) as autonomous forecasting agents on real, future events. For every one of the 104 matches of the 2026 FIFA World Cup, four frontier models -- Claude Opus 4.8, ChatGPT (GPT-5.5, high reasoning), Gemini 3.1 Pro, and Grok (Expe...
Jiachen Ding, Congyu Guo, Jason Xu· arXiv.org· 1 citation
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