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Author

Jayda G. Eldiasty

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Open access 2026

Integrated Transcriptomic Analysis of Human Neural Progenitor Cells Reveals Key Pathways and Therapeutic Targets in Fragile X Syndrome

Fragile X syndrome (FXS), caused by the silencing of the FMR1 gene, is characterized by synaptic defects in mature networks. This study aims to elucidate early transcriptomic abnormalities in human FXS neural progenitor cells (NPCs) to uncover pre-synaptic mechanisms of the disease. An integrated transcriptomic re-...

H. Alatawi, Jayda G. Eldiasty · 0 citations
Review Aug 2026

Unlocking the epigenetic code: future Frontiers in predictive biomarkers for intellectual disability in fragile X syndrome.

This review critically evaluates the shift from traditional genetic screening to advanced epigenetic profiling as a robust framework for predicting ID in FXS and outlines a strategic roadmap for standardizing epigenetic assays, highlighting their potential to revolutionize the predictive landscape of neurodevelopmental...

Hanan Ali Alatawi, Jayda G. Eldiasty · 0 citations

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