Integrated Transcriptomic Analysis of Human Neural Progenitor Cells Reveals Key Pathways and Therapeutic Targets in Fragile X Syndrome
Fragile X syndrome (FXS), caused by the silencing of the FMR1 gene, is characterized by synaptic defects in mature networks. This study aims to elucidate early transcriptomic abnormalities in human FXS neural progenitor cells (NPCs) to uncover pre-synaptic mechanisms of the disease. An integrated transcriptomic re-...