Preprint
Sep 2026
Enhancer-promoter proximity predicts transcriptional competence but not transcriptional output in the Drosophila brain
How 3D genome architecture contributes to transcriptional specificity across neuronal cell types remains unclear. Here, we used multiplexed chromatin tracing to map chromatin architecture and cell identity at single-cell resolution in the adult Drosophila brain. We found that enhancer-promoter (E-P) proximity was incre...
Olivier Messina, Loucif Remini, Christopher H. Bohrer et al.
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