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Author

Jennifer Keiser

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Review Open access Aug 2026

Early-stage anthelmintic discovery: Integrating phenotype, target and mechanism.

Parasitic helminth infections impose major burdens on human and animal health, and increasing anthelmintic resistance reinforces the need for new drugs. Early-stage discovery remains constrained by the scarcity of novel, potent, selective and chemically tractable starting points, the limited predictive value of some ex...

A. Taki, B. Sleebs, Timothy N C Wells et al. · 0 citations
Open access Aug 2026

Chemical perturbation reveals a cytoskeletal–trafficking vulnerability in Haemonchus contortus

It is indicated that linked structural and proteolytic responses contribute to chemical sensitivity in H. contortus and how integrative proteomics can resolve organism-level responses to chemical perturbation beyond single-target paradigms is demonstrated.

A. Taki, Nghi H. Nguyen, Tao Wang et al. · 0 citations

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