Open access
Sep 2026
Discovery and engineering of bispecific TCR-mimic antibodies targeting peptide–HLA complex
An integrated platform for generating human antibodies that mimic T-cell receptors and recognize peptide-HLA complexes with high specificity and affinity is developed, demonstrating superior performance compared to competitors’ TCRm antibodies.
Jennifer Watkins-Yoon, Wei-Cheng Lu, E. Petrunak et al.
· mAbs · 0 citations