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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Jennitte L. Stevens

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Open access Sep 2026

SEC-seq reveals translation-focused metabolic strategies for high IgG productivity in clonal CHO cells.

Chinese hamster ovary (CHO) cells are the dominant host for therapeutic protein production, yet intra- and inter-clonal heterogeneity in manufacturing phenotypes, and the underlying metabolic and secretory circuitry, remain poorly defined at single-cell resolution. Using secretion encoded single-cell sequencing (SEC-se...

Jasmine Tat, Fides D. Lay, Jennitte L. Stevens et al. · 0 citations

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