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Jenny Brodbelt

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Open access Aug 2026

A Quantitative Two-Channel Genetic Reporter for Selenocysteine Biosynthesis and Incorporation

Selenocysteine (Sec), the 21st amino acid, is a rare non-canonical amino acid that represents an attractive target for protein engineering due to its desirable chemical properties such as high affinity for metals, strong nucleophilicity, and reversible covalent bond formation. To bypass the natural constraints on Sec p...

Andrew R. Gilmour, Qiyao Wei, Jessica Hellinger et al. · 0 citations

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