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Author

Jens B. Bosse

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Open access Sep 2026

Variant-specific nucleocapsid mutations shape host innate immune trajectories during SARS- CoV-2 infection

It is found that the mutations induce distinct transcriptional and translational alterations: rN-Alpha drives a stealth-like infection characterized by sustained translation efficiency and specific evasion of the 2’-5’-oligoadenylate synthetase (OAS) innate immune sensor, whereas rN-Delta and rN-BA trigger a highly ele...

J. Berger, Jonas Schröder, Timothy K. Soh et al. · 0 citations
Open access Aug 2026

Virion-wide interactome mapping of HSV-1 reveals maturation-dependent remodeling and convergent organization of herpesvirus tegument networks

A virion-wide spatial and quantitative protein proximity map of herpes simplex virus 1 (HSV-1) is defined by combining cross-linking mass spectrometry with quantitative proteomics, showing how conserved organizational principles shape virus-specific virion interaction networks during herpesvirus maturation.

Lars Mühlberg, Yannick Jensen, Julia Ruta et al. · 0 citations

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