Open access
Jul 2026
In vivo and ex vivo impact of THBD and PROCR polymorphisms on the anticoagulant response of the protein C pathway.
In vivo evidence is provided that common THBD and PROCR variants modulate PC pathway function, establishing the APC response as a sensitive endpoint for subtle genetic effects beyond FVL and not associated with THBD 1418C>T.
S. Reda, N. Schwarz, Sebastian Eckert et al.
· Blood Advances · 0 citations