Author

Jeong Seok Lee

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Open access Sep 2026

Alveolar epithelial depletion of βPAK-interacting exchange factor drives spontaneous pulmonary fibrosis by impairing stemness

Aberrant repair/regeneration of alveolar epithelial stem cells is a key driver of pulmonary fibrosis (PF). While βPAK-interacting exchange factor (βPIX) is connected to stem cell signaling, its role in pulmonary fibrosis (PF) remains unknown. Here, we generated conditional βPIX knockout mice to investigate its contribu...

Han-Byeol Kim, Woogil Song, Sun-Ok Kim et al. · Signal Transduction and Targ... · 0 citations

Open access Jul 2026

Integrated peripheral immune profiling reveals B-cell dysregulation and CD8 effector signatures in chronic inflammatory demyelinating polyneuropathy

Background Chronic inflammatory demyelinating polyneuropathy (CIDP) is an immune-mediated peripheral neuropathy with heterogeneous and often incomplete responses to current immunotherapies, but the underlying immune basis remains poorly defined. Although CIDP shares features of immune-mediated demyelination with multip...

Hyunjin Kim, Jinhui Chun, D. Cha et al. · Frontiers in Immunology · 0 citations